Ondemand continuousflow production of pharmaceuticals in

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On-demand continuous-flow production of pharmaceuticals in ...

Pharmaceutical manufacturing typically uses batch processing at multiple locations. Disadvantages of this approach include long production times and the potential for supply chain disruptions. As a preliminary demonstration of an alternative approach, we report here the continuous-flow synthesis and

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On-demand continuous-flow production of pharmaceuticals in ...

Pharmaceutical manufacturing typically uses batch processing at multiple locations. Disadvantages of this approach include long production times and the potential for supply chain disruptions. As a preliminary demonstration of an alternative

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On-Demand Continuous Flow Production of Pharmaceuticals in ...

Request PDF On-Demand Continuous Flow Production of Pharmaceuticals in a Compact, Reconfigurable System Pharmaceutical manufacturing typically uses batch processing at multiple locations.

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On-demand continuous-flow production of pharmaceuticals in ...

Request PDF On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system Pharmaceutical manufacturing typically uses batch processing at multiple locations ...

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Generic DART-MS platform for monitoring the on-demand ...

Apr 15, 2017  1. J Pharm Biomed Anal. 2017 Apr 15;137:243-251. doi: 10.1016/j.jpba.2017.01.050. Epub 2017 Jan 29. Generic DART-MS platform for monitoring the on-demand continuous-flow production of pharmaceuticals: Advancing the quantitative protocol for caffeates in microfluidic biocatalysis.

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Advanced Continuous Flow Platform for On-Demand ...

As a demonstration of an alternative to the challenges faced with batch pharmaceutical manufacturing including the large production footprint and lengthy time-scale, we previously reported a refrigerator-sized continuous flow system for the on-demand production of essential medicines. Building on th

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On-Demand Drug Production Is on the Horizon - Scientific ...

Apr 01, 2016  The paper, by A. Adamo at Massachusetts Institute of Technology in Cambridge, MA, and colleagues was titled, ‘On-demand continuous-flow production of pharmaceuticals in

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Generic DART-MS platform for monitoring the on-demand ...

Apr 15, 2017  Today, continuous processing is regarded as an effective on-demand production technique of pharmaceuticals. Homemade microreactors packed with immobilized lipase under continuous-flow conditions were first applied to tailor the production of high-value caffeic acid phenethyl ester (CAPE) from methyl caffeate (MC) and 2-phenylethanol (PE) in cyclohexane via transesterification; however, this ...

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“Pharmacy on Demand” To Revolutionize Drug Manufacturing ...

“On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system” By Andrea Adamo, et al., American Association for the Advancement of Science, April 1, 2016, Vol. 352, No. 1681, p. 62.

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Media On Demand Pharmaceuticals

Advanced continuous flow platform for on-demand pharmaceutical manufacturing. Chemistry- A European Journal (January 31, 2018) On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system. Science (April 1, 2016) Pharmacy on demand: New technologies to enable miniaturized and mobile drug manufacturing.

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On-Demand Continuous Flow Production of Pharmaceuticals in ...

Request PDF On-Demand Continuous Flow Production of Pharmaceuticals in a Compact, Reconfigurable System Pharmaceutical manufacturing typically uses batch processing at multiple locations.

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On-demand continuous-flow production of pharmaceuticals in ...

Request PDF On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system Pharmaceutical manufacturing typically uses batch processing at multiple locations ...

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On-demand continuous-flow production of pharmaceuticals in ...

Drug manufacturing in a fridge-sized box Commodity chemicals tend to be manufactured in a continuous fashion. However, the preparation of pharmaceuticals still proceeds batch by batch, partly on account of the complexity of their molecular structures. Adamo et al. now present an apparatus roughly the size of a household refrigerator that can synthesize and purify pharmaceuticals under ...

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On-demand continuous flow production of pharmaceuticals in ...

Title : On-demand continuous flow production of pharmaceuticals in a compact, reconfigurable system: Language : English: Author, co-author : Adamo, Andrea [Massachusetts Institute of Technology - MIT > Chemical Engineering > > >]: Beingessner, Rachel L. [Massachusetts Institute of Technology - MIT > Chemistry > > >] Behnam, Mohsen [Massachusetts Institute of Technology - MIT > Chemical ...

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Science-2016-On-demand continuous-flow production of ...

Apr 01, 2016  Science-2016-On-demand continuous-flow production of pharmaceutical.. Chinnery,Cochrane Database Syst. Rev. CD004426(2012). Neuropathol.Exp. Neurol. 74, 482–492 (2015). ... accepted February2016 Published online 25 February 2016 10.1126/science.aad9642 FLOW CHEMISTRY On-demand continuous-flow production compact,reconfigurable system Andrea ...

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Advanced Continuous Flow Platform for On-Demand ...

As a demonstration of an alternative to the challenges faced with batch pharmaceutical manufacturing including the large production footprint and lengthy time-scale, we previously reported a refrigerator-sized continuous flow system for the on-demand production of essential medicines. Building on th

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On-demand continuous-flow production of pharmaceuticals in ...

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system Autores: Andrea Adamo , Rachel L. Beingessner , Mohsen Behnam , Jie Chen Localización: Science , ISSN 0036-8075, Vol. 352, Nº 6281, 2016 , págs. 61-67

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On-Demand Drug Production Is on the Horizon - Scientific ...

Apr 01, 2016  The paper, by A. Adamo at Massachusetts Institute of Technology in Cambridge, MA, and colleagues was titled, ‘On-demand continuous-flow production of pharmaceuticals in

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'Pharmacy on Demand' To Revolutionize Drug Manufacturing ...

3 “On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system” By Andrea Adamo, et al., American Association for the Advancement of Science, April 1, 2016, Vol. 352, No. 1681, p. 62. 4 Bebinger, May 26, 2016. 5 “Inventing a Machine That Spits Out Drugs in a Whole New

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Media On Demand Pharmaceuticals

Advanced continuous flow platform for on-demand pharmaceutical manufacturing. Chemistry- A European Journal (January 31, 2018) On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system. Science (April 1, 2016) Pharmacy on demand: New technologies to enable miniaturized and mobile drug manufacturing.

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“Pharmacy on Demand” To Revolutionize Drug Manufacturing ...

“On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system” By Andrea Adamo, et al., American Association for the Advancement of Science, April 1, 2016, Vol. 352, No. 1681, p. 62.

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Research: Pharmacy on Demand (PoD) – Jensen Research Group

“On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system,” Science. 352, 61-67 (2016). Recent Publications " A graph-convolutional neural network model for the prediction of chemical reactivity ,” Chem. Sci. .

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Generic DART-MS platform for monitoring the on-demand ...

Apr 15, 2017  Today, continuous processing is regarded as an effective on-demand production technique of pharmaceuticals. Homemade microreactors packed with immobilized lipase under continuous-flow conditions were first applied to tailor the production of high-value caffeic acid phenethyl ester (CAPE) from methyl caffeate (MC) and 2-phenylethanol (PE) in cyclohexane via transesterification; however, this ...

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CONTINUUS Pharmaceuticals Home

CONTINUUS Pharmaceuticals is a spin-out company from a multi-year collaboration between MIT and Novartis on Continuous Manufacturing. We specialize in end-to-end Integrated Continuous Manufacturing (ICM), with the application of novel process technologies that enable rapid production of pharmaceuticals at significantly reduced costs and better ...

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On-demand continuous-flow production of pharmaceuticals in ...

Pharmaceutical manufacturing typically uses batch processing at multiple locations. Disadvantages of this approach include long production times and the potential for supply chain disruptions. As a preliminary demonstration of an alternative

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On-demand continuous-flow production of pharmaceuticals in ...

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system Autores: Andrea Adamo , Rachel L. Beingessner , Mohsen Behnam , Jie Chen Localización: Science , ISSN 0036-8075, Vol. 352, Nº 6281, 2016 , págs. 61-67

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Pharmacy on demand: Portable system can be configured to ...

Mar 31, 2016  On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system. Science , 2016; 352 (6281): 61 DOI: 10.1126/science.aaf1337 Cite This Page :

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Advanced Continuous Flow Platform for On‐Demand ...

Jan 31, 2018  As a demonstration of an alternative to the challenges faced with batch pharmaceutical manufacturing including the large production footprint and lengthy time-scale, we previously reported a refrigerator-sized continuous flow system for the on-demand production of essential medicines.

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On Demand Pharmaceuticals, Inc.: Senior Scientist

pharmaceutical supply chain and enable local production of medicines. This position will be responsible for: Develop new synthetic methodologies in batch and flow Working on the development and translation of new drugs onto the next generation of “Pharmacy on Demand” manufacturing platforms that

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The case for nanoparticles - Pharmaceutical Manufacturing

Oct 14, 2020  Continuous production methods enable miniaturization that was previously not possible. To demonstrate this, researchers at Massachusetts Institute of Technology designed an on-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system around the size of a refrigerator.

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Pharmacy on demand MIT News Massachusetts Institute of ...

Mar 31, 2016  “Sometimes it’s very difficult to get those drugs, because economically it makes no sense to have a huge production operation for those,” Jensen says. It could also be useful in regions with few pharmaceutical storage facilities, because drugs can be produced on

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制药业的革命?《Science》报道仅冰箱大小的全自动药物生产机

Apr 06, 2016  (On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system. Science, DOI: 10.1126/science.aaf1337) Klavs F. Jensen教授。图片来源:MIT. 这种连续流药物生产系统比传统的设备小得多,而且更便宜。

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MIT Researchers Aim To Create An On-Demand Pharmacy WBUR

May 16, 2016  Myerson, Jamison and Jensen said they expect to seek FDA approval in two years or so for their pharmaceuticals-on-demand unit. By then, it may be even smaller, the size of dorm fridge, and be ...

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Naomi Briggs - VP of Research Development - On Demand ...

Director of Drug Substance Purification for On Demand Pharmaceuticals, a start-up company tasked with commercializing the Pharmacy on Demand (POD) technology, developed at MIT, through the ...

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A compact, portable, re-configurable, and automated system ...

Mar 25, 2018  On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system Science , 352 ( 2016 ) , pp. 61 - 67 CrossRef View Record in Scopus Google Scholar

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End-to-end continuous manufacturing of conventional ...

May 15, 2020  On-demand continuous-flow production of pharmaceuticals in a compact reconfigurable system Science , 352 ( 2016 ) , pp. 61 - 67 , 10.1126/science.aaf1337 CrossRef View Record in

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Compact drug synthesizer could revolutionize EurekAlert!

Mar 31, 2016  The paper, by A. Adamo at Massachusetts Institute of Technology in Cambridge, MA, and colleagues was titled, 'On-demand continuous-flow production of pharmaceuticals in a

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อ.นพพล.docx - Google Docs

On-demand Continuous-flow Production of Pharmaceuticals in a Compact, Reconfigurable System. Science , 352 (6281), pp. 61-67. (*All authors are listed in alphabetical order).

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